Melamet cream, is it safe? uses & side-effects

What is Melamet Cream ?

Melamet Cream is a branded medicated cream, usually prescribed for the treating and lightening dark skin spots,wrinkles and acne on skin. This cream is manufactured and marketed by UTH HEALTH CARE. This cream is available in the packaging of 15 gm per tube.

  1. What is the generic name(s)?
  2. How does it work ?
  3. What are it’s uses ?
  4. How effective is this medicine ?
  5. What are the Side Effects ?
  6. Is this medicine addictive?
  7. What happens if it over-applied and how to manage? ?
  8. What to do in case there is an allergic reaction with it? ?
  9. What is the Dosage ?
  10. What are the precautions I need to take ?
  11. Is it safe to use if I am pregnant ?
  12. Is it safe to use if I am breast feeding ?
  13. Can this medicine be used for children and infants ?
  14. Is Melamet Cream available as an over the counter (OTC) product?
  15. Frequently asked questions
  16. Reference


Melamet Cream

Melamet Cream – uses & side-effects


What is the generic name (s)?

Melamet Cream has combination of three active substituents in composition in % w/w is being described below

  • Hydroquinone[1] – 2 %W/W
  • Mometasone[2] furoate – 0.1%W/W
  • Tretinoin[3] – 0.025 %W/W

How does it work ?

Tretinoin belong to class of retiniods[4] which helps prevent  or reduce the intensity of acne[5] or treat acne and wrinkles[6] by peeling off dead skin cells or by stopping the growth of skin[7] cells.

Hydroquinone is skin bleaching agent  which lightens skins where hyperpigmentation[8] has occured like pregnancy  marks , chloasma[9], melasma[10], freckles, this works by stoping the skin coloring agents and bleaching action

Cortisone is adrenocortical steroids and anti-allergy treats or reduces inflammation ,swelling, itching, and redness by stopping inflamation causing factors.

What are it’s uses ?

Melamate cream useful in the management of the following medical conditions:

This cream is used in the

prevention, control and treatment of lightining of dark patches and dark skin, Age spots, Acne vulgaris, Topical Acne, wrinkles, lightning pregnancy marks, melasma,freckles etc.,

How effective is this medicine ?

Melamet Cream is a very effective topical cream for all the conditions mentioned above. It is used in the correct way for the suggested period and frequency as advised by an expert. For best results make sure to follow the instructions on how to use the product provided on the product.

What are the Side Effects ?

Some commonly reported side-effects of generic components of Melamet cream are being described below:

  • Scaling and mild burning
  • Skin redness due to allergic reaction
  • Itching
  • Tenderness in the skin
  • Soreness
  • Mild skin irritation
  • Inflammation, burning
  • Erythema & stinging
  • Changes in color of skin
  • Burning
  • Dryness in the skin
  • Stinging
  • Facial swelling
  • Blisters at the cream applied area
  • Darkening of the color of the skin
  • Thickening of the skin
  • Reaction at the cream applied area

Though the side effects due to interactions of the individual ingredients of skinlite cream are not known, below are the side effects of the individual ingredients:

Hydroquinone : Some of the side effects of hydroquinone include Mild skin irritation, burning, erythema & stinging. Hydroquinone has been linked to ochronosis (skin darkening and disfiguration).This product has a weaker formula i.e., 2% compared to 4% in the prescription creams like Lustra, Tri-Luma, and EpiQuin Micro, so it is relatively safe when used for short duration.

Hydroquinone has been on cancer watch list of FDA and it’s usage has been quite controversial, especially because life time usage of hydroquinone on animals has been linked to increased risk of cancer due to ochronosis. Reportedly there are no cancer cases in human beings linked to hydroquinone till date, so weaker strength (0.5% to 2%) Hydroquinone is still available in some of the over the counter products, while stronger (4%) Hydroquinone is only available on prescription.

Tretinoin: Some of the side effects of Tretinoin are skin redness, itching , scaling and mild burning. Initially when you start applying Tretinoin on your skin, it will worsen the acne in first 2 – 4 weeks, this will taper with continued usage. As Tretinoin will make your skin dry, it is suggested that you use a good moisturiser in the day time.

Mometasone furoate : Some of the side effects of Mometasone furoate include, burning, itching and stinging, but these generally last for a short time.

If any of these side effects persist longer, consult a dermatologist immediately.

Is Melamet Cream addictive?

Habit forming tendencies for this medicine has not been reported. Most medicines don’t come with a potential for addiction. Government  also categorizes medicines that can be addictive as controlled substances. Finally,  do not self-medicate and increase your body’s dependence to medicines without taking the advice of a doctor.

What happens if Melamet Cream over-applied and how to manage?

It is not recommended to use more than the prescribed dose. Taking more than the prescribed dose will not improve your symptoms,  it may cause serious side-effects. If you suspect that you or anyone else who may have overdose, please go to the emergency department of the closest hospital. Do not give your used medicines to others. Please consult your physician or pharmacist or product package for more information.

 What to do in case there is an allergic reaction with Melamet Cream?

Some of the side effects of this medicine are skin irritation, rashes, and Inflammation.If you observe any of the above side effects, gently clean the affected area with cold  water and  have a cold compress on the affected area.  Consult your doctor as soon as possible and take necessary remedies.

What is the Dosage ?

The quantity of Melamet cream to be applied for the particular skin condition and also the frequency of application per day has to be as per Dermatologist’s prescription. Also, one must not exceed the duration (in terms of number of days) of the use of this cream.

Cream - Dosage

Cream – Dosage

What are the precautions I need to take ?

While using Betnovate C cream precaution should be exercised:

  • This is cream for external use only
  • Avoid inhaling and swallowing
  • Avoid contact with mouth and eyes
  • Be sure that the patient is not allergic to any of the component of this cream
  • Avoid covering the affected are with bandage etc. to prevent internal absorption in the skin
  • Monitor actively if being used for long-term
  • Avoid if the patient has acute and/or systemic fungal infection
  • Usage has to be withdrawn slowly
  • Use with caution if the patient is an elderly person
  • Use with caution with patients(especially women), who have recently undergone a thyroid test

Is it safe to use if I am pregnant ?

For topical application this medicine is relatively safe to use during pregnancy, but should be used only if clearly needed.
Please do not self-medicate with this cream.

Is it safe to use if I am breast feeding ?

This medicine is relatively safe to use while breast feeding , but should not be applied any where near breast. Make sure the baby doesn’t come in to contact with the cream and use this medicine only when clearly needed.

Consult a doctor to know if this cream is safe for you.

Can this medicine be used for children and infants ?

This medicine should not be used for Children and infants and should be kept out of their reach.



Is Melamet Cream available as an over the counter (OTC) product?

Yes, this medicine is available as an over the counter product, but it is suggested that you consult a dermatologist to know if you can use this medicine on your skin.

Frequently asked questions

Can this cream be used on face?
Yes this cream can be used on face. But it is advised that the continuous usage should not be more than 5 days.

Can this cream cause skin-pigmentation or change in skin color?
Yes, this cream can cause skin-pigmentation in some patients. It can both lighten or darken the color of skin.

Can I apply this cream on open wounds ?
No, this cream is for External use only. Applying this cream on open wound can worsen the injury and may also generate infections.

How one should store this cream ?
This cream should be stored in an air-tight container at room temperature, protected from heat. Please keep it away from the reach of children and pets.Also, discard the remaining medicine after its expiry date has passed.

Can I apply it as many times I want in a day?
No, that will be harmful for the skin. Generally it is advised to be used twice or thrice in a day. Please follow your dermatologist’s instructions on this.

How long this cream can be used continuously?
This cream should not be used for more than 4 weeks straight in a row. Please follow your dermatologist’s instruction on this.

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