Nicip plus, is it safe ? uses, side-effects, dosage

What is Nicip plus ?

Nicip Plus is an oral prescription medicine used in the treatment of fever, headache and pains. It is a combination of painkiller and anti-inflammatory drugs. This medicine is manufactured by Cipla Ltd. The medicine is available in market in packaging of 10 tablets per strip.

  1. What is the generic name(s)?
  2. How does it work ?
  3. What are it’s uses ?
  4. How effective is this medicine ?
  5. What are the Side Effects ?
  6. What is the Dosage ?
  7. What are the precautions I need to take ?
  8. Is it safe to take if I am pregnant ?
  9. Is it safe to take if I am breast feeding ?
  10. Can this medicine be given to children and infants ?
  11. Is Nicip plus available as an over the counter (OTC) product?
  12. Frequently asked questions
  13. Reference


Nicip plus - uses, side-effects, dosage

Nicip plus – uses, side-effects, dosage

What is the generic name (s)?

Nicip plus tablet contains two active ingredients. The composition of the ingredients is listed below:

  • Nimesulide —————- 100 mg
  • Paracetamol ————– 325 mg

Nimesulide is an nonsteroidal anti-inflammatory drug (NSAID). It helps in relieving pain and swelling.
Paracetamol is an anti-pyretic and analgesic drug. It is used in treatment of fever and pain.

How does it work ?

Nimesulide reduces the production of a chemical called prostaglandins. This chemical causes swelling and pain in body. The drug blocks the production and action of prostaglandins and relives the body pain and swelling.

Paracetamol has both anti-pyretic and painkilling properties. It works by stimulating the brain’s temperature-regulating region and increasing the pain threshold. Paracetamol increases the blood flow across the skin. It results in sweating, heat loss and helps in lowering the fever.

What are it’s uses ?

This medicine is majorly used in the prevention, control and treatment of the following diseases and conditions:
  • Ear pain
  • Tooth pain and pain in jaws
  • Headache
  • Joint pain
  • Heavy menstrual pain and abdominal cramps (Dysmenorrhea)
  • Cold and flu
  • Fever
  • Short term pain in any part of body
  • Acute pain
  • Leg pain due to inflammation in wall of a vein during pregnancy (Thrombophlebitis)
  • Osteoarthritis
  • Rheumatoid arthritis

How effective is this medicine ?

Nicip plus tablet is very effective in the management of all the pain, fever and inflammatory disorders as mentioned above. One should use it after discussing the condition and other symptoms with a qualified doctor.

What are the Side Effects ?

The following list is a comprehensive list of all the possible side effects of this drug. Some of the side effects may occur very rarely. If you experience any of these side effects, Inform your doctor immediately .

  • Allergic reactions, papilations
  • Diarrhea, Vomiting and nausea
  • Abnormality in blood cells and blood count
  • Anemia
  • Acute renal tubular necrosis
  • Breathlessness, shortened breath, and Anxiety
  • Muscular weakness, Dizziness
  • Platelet deficiency in blood
  • Rashes, Blister or bullae on skin
  • Irritation and itching
  • Abdominal pain, Constipation, gas and other GI disorders
  • Headache, heartburn and acidity
  • High blood pressure and hypersensitivity
  • Liver toxicity, Liver damage and increased level of liver enzymes
  • Swelling of ears and eyes, rashes and itching on face

Consult your doctor if you develop any other medical conditions while using this medicine.

What is the Dosage ?

The dosage of Nicip plus should be as prescribed by the doctor. This also varies with patient’s age and the medical condition being managed. Please consult with the doctor regarding the course and duration of administration of this medicine.

Generally, an adults may be prescribed with 2 tablets per day. The medicine is not advised for minors and elderly patients.

Tablet - dosage

Tablet – dosage

What are the precautions I need to take ?

While using Nicip plus tablets following precaution should be exercised:

  • Don’t take this tablets if you are allergic to Paracetamol or Nimesulide, or any of the other incipients of the drug.
  • Do not this tablets if you had been or currently suffering from gastric bleeding and ulcers.
  • Women should avoid the long-term or regular use of this medicine as Nimesulide can cause infertility in women.
  • Do not take this medicine if you have or had serious liver and kidney impairments in the past.
  • Never consume more than the prescribed amount the medicine.
  • Do not take this medicine if you are on other medications.
  • Never take two different painkiller medicines at once.
  • Discuss your medical history and condition with a doctor before using this tablets.

Is it safe to take if I am pregnant ?

Yes, it is safe to take Nicip plus tablet if you are pregnant or planning to get pregnant.

This drug is classified by FDA as pregnancy category ‘B’ No risk in other studies: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Consult your gynecologist before administering this drug. Please, do not self-medicate.

Is it safe to take if I am breast feeding ?

No, this medicine is not safe to take if you are breast feeding or planning to start breast feeding. There are strong evidences that this drug is secreted through breast milk. It can harm the infant an affect the production and quality of breast milk.

Please consult your doctor before using this medicine if your nursing a baby.

Can this medicine be given to children and infants ?

No, this tablets can not be given to children below 12 years of age.

Nimesulide is banned from use in the United States of America. In India it can only be prescribed to patients which are older than 12 years of age.

Always consult a doctor before administering this medicine.

Is Nicip plus available as an over the counter (OTC) product?

No, Nicip Plus tablet is not available as an over the counter (OTC) product. It is a prescription drug. It has to be prescribed by a qualified specialist only.

Frequently asked questions

Missed a dose of Nicip plus, what should I do ?

In case you missed a dose, you can take it  as soon as you remember about it. But if it is close to the time of next dose, skip the missed dose and continue the routine with next dose.
Do not take double dose/ overdose of this medicine. Taking extra dose will not improve your symptoms and condition, rather it may cause serious side effects and medicinal poisoning.

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