Progyluton, is it safe? Uses, side-effects, dosage

What is Progyluton?

Progyluton is a branded oral tablet formulation, manufactured and marketed by Bayer Schering Pramaceuticals limited. This drug is a combination of Estradiol and Norgestrel and is prescribed to prevent ovulation. This drug is available in a cyclic tablet dispenser of 21 tablets.

  1. What is the generic name(s)?
  2. How does it work ?
  3. What are it’s uses ?
  4. How effective is this medicine ?
  5. What are the Side Effects ?
  6. What is the Dosage ?
  7. What are the precautions I need to take ?
  8. Is it safe to take if I am pregnant ?
  9. Is it safe to take if I am breast feeding ?
  10. Can this medicine be given to children and infants ?
  11. Is Progyluton available as an over the counter (OTC) product?
  12. Frequently asked questions
  13. Reference
Progyluton - uses, side-effects, dosage

Progyluton – uses, side-effects, dosage

What is the generic name (s)?

The generic medicines present in Progyluton are Estradiol valerate and norgestrel.
One strip of progyluton contains 11 White tablets and 10 red tablets. Composition of these hormones per tablet is as followed:

  • White Tablets – Estradiol valerate 2 mg each tablet
  • Red Tablets – Estradiol valerate 2 mg and norgestrel 0.5 mg each tablet

How does it work ?

Progyluton is a combined Hormonal medicine. Estradiol valerate is a synthetic form of female hormones responsible for the maintenance and development of menstruation cycles. While Norgestrel is a hormone which stops the ovulation and prevent egg from fertilization. The combination of these 2 hormones make Progyluton a very safe hormone replacement medicine.

What are it’s uses ?

This medicine is a used in the treatment of irregular menstruation and abnormal uterine bleeding.

How effective is this medicine ?

These tablets are very effective and safe option, if taken regularly in proper cycle.

What are the Side Effects ?

Commonly reported side-effects from new users of this medicine includes following :

  • Lower Stomach pain
  • Delayed menstruation
  • Sudden bleeding/ spotting
  • Breast tenderness
  • Acne and pimples
  • Nausea
  • Water retention
  • Weight gain
  • Mood swings

All these symptoms are temporary and disappear overtime with regular use of these tablets.

However, in some cases this drug can cause serious implications. Consult your doctor immediately if you are facing any of the following issues after the use of this medicine:

  • Uterine hemorrhage
  • Infections in uterus
  • Unusual tiredness
  • Vomiting with weakness and nausea
  • Excessive vaginal bleeding
  • Gasrto-intestinal cramps
  • Severe headache and Anxiety

What is the Dosage ?

The dosage for these tablets begin with 1 tablet from the first day of Menstrual cycle. Then one tablet each day for 20 days, followed  by 7 days without taking the tablet.
If you want to continue the course of this medicine again, start with the new strip from 8th day since you took the tablet last.

Tablet - dosage

Tablet – dosage

What are the precautions I need to take ?

You should not take this medicine in following situations

  • If you have ever had a clot in a blood vessel, or any circulation problems in the past.
  • If you are breast-feeding or think you may be pregnant.
  • If you are a smoker, consult your doctor before taking this medicine.
  • If you have a breast lump or had breast cancer in the past.
  • Don’t take this medicine if you are suffering from high blood pressure.
  • This medicine should be avoided for patients with depression.
  • If you have gallstones or liver dysfunction .
  • If you are suffering from cardiac problems, diabetes, or migraine.
  • If you had a transient ischemic attack in the past.
  • If you have any vaginal bleeding other than your normal menstrual period.

Is it safe to take if I am pregnant ?

This drug is classified by FDA as pregnancy category ‘X’ Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Consult a doctor before administering this medicine to a pregnant woman.

Is it safe to take if I am breast feeding ?

It can be unsafe to take if you are breast feeding or are planning for breast feeding. Consult with a doctor if you are breastfeeding or planning to start breastfeeding before using this medicine.

Can this medicine be given to children and infants ?

This medicine should not be given to children and infants. Keep this tablet away from the reach of children. If a child accidentally takes this tablet, rush him immediately to your doctor.

Is Progyluton available as an over the counter (OTC) product?

No, This drug is not available as an over the counter product and requires a prescription from a doctor.

Frequently asked questions

Can I take Progyluton medicine as a Contraceptive?
No, This medicine can not be taken as a Contraceptive. The level of hormones are very low this medicine and it will not be able to avoid unplanned pregnancy.

Can I take Oxcarbazepine, while on Progyluton medication ?
No, both norgestrel and estradiol valerate have major interactions with Oxcarbazepine and Oxcarbazepine may reduce the blood levels and effects of both norgestrel and estradiol, ask your doctor for a prescription of different medicine.

What to do if I forget to take a pill of this medicine ?
In case you forgot to take one pill during course of Progyluton, take it as soon as you remember Continue the dosage with next pill at normal schedule.
If more than 12 hours had passed since the scheduled time of taking the pill you missed, then follow the instructions below:
Case 1: If it happens in 1st or 2nd week of pills, use extra precautions for the next 7-8 days.
Case 2: If you missed to take a pill in the last week of cycle, start the next course of dosage straightaway and do not have a pill-free week. No extra precautions needed, finish the newly started course normally. At the end of the cycle, stop and have a break as normal.

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