Tri Sprintec, is it safe ? uses, side effects, dosage

What is Tri Sprintec

Tri Sprintec is a branded oral contraceptive formulation, manufactured and marketed by Barr Laboratories Inc. This drug is a combination of estrogen and progestin and is prescribed to prevent ovulation. This drug is available in a cyclic tablet dispenser of 28 tablets.

  1. What are the Generic Name(s)
  2. How does it work ?
  3. What are it’s uses ?
  4. How effective is this medicine ?
  5. What are the Side Effects ?
  6. What is the Dosage ?
  7. What are the precautions I need to take ?
  8. Is it safe to take If I am pregnant ?
  9. Is it safe to take if I am breast feeding ?
  10. Can this medicine be given to Children and Infants ?
  11. Is Tri Sprintec available as over the counter (OTC) product?
  12. Frequently asked questions
  13. Reference


tri sprintec uses, side-effects, dosage

tri sprintec uses, side-effects, dosage

What are the Generic Name(s)

Generic name of tri sprintec is norgestimate and ethinyl estradiol, each gray tablet contains 0.18 mg norgestimate and 0.035 mg ethinyl estradiol.

Some of the other branded alternatives of this drug are Ortho-Cyclen, Tri-Previfem, Tri-Linyah, Previfem, Sprintec, TriNessa, Mononessa, Ortho Tri-Cyclen, Tri-Estarylla, Estarylla, Mono-Linyah, Tri-Lo-Marzia.

How does it work ?

This drug contains estrogen and progestin, which are female sex hormones. Combinations of estrogen and progestin work by preventing ovulation. It changes the lining of uterus to prevent pregnancy and also changes the mucus at the cervix preventing the sperm from entering it.

What are it’s uses ?

Tri sprintec is an oral contraceptive and it is generally prescribed to prevent pregnancy and in some cases this drug is also prescribed for the treatment of acne to some patients.

How effective is this medicine ?

This drug is very effective in preventing pregnancy, if taken in quantity and frequency as prescribed by the doctor.

What are the Side Effects ?

Some of the reported side effects of this drug include :

  • nausea
  • vomiting
  • stomach cramps or bloating
  • diarrhea
  • hair growth in unusual places
  • bleeding or spotting between menstrual periods
  • increased or decreased appetite
  • constipation
  • gingivitis (swelling of the gum tissue)
  • acne
  • weight gain or weight loss
  • brown or black skin patches
  • breast tenderness, enlargement, or discharge
  • swelling, redness, irritation, burning, or itching of the vagina
  • white vaginal discharge
  • changes in menstrual flow
  • painful or missed periods

Very rarely reported , adverse effects of this drug include:

  • severe headache
  • severe vomiting
  • speech problems
  • dizziness or faintness
  • weakness or numbness of an arm or leg
  • swelling of the hands, feet, ankles or lower legs
  • depression, especially if you also have trouble sleeping, tiredness, loss of energy, or other mood changes
  • unusual bleeding
  • rash
  • menstrual bleeding that is unusually heavy or that lasts for longer than 7 days in a row
  • pain during sexual intercourse
  • thick, white curd-like vaginal discharge without odor or with mild odor
  • coughing up blood
  • shortness of breath
  • pain, warmth, or heaviness in the back of the lower leg
  • partial or complete loss of vision
  • double vision
  • bulging eyes
  • crushing chest pain or chest heaviness
  • loss of appetite
  • extreme tiredness, weakness, or lack of energy
  • fever
  • dark-colored urine
  • light-colored stool
  • severe stomach pain
  • yellowing of the skin or eyes

If any of the side effects persist or if you observe any of the serious side effects, seek emergency medical help or consult a doctor immediately.

What is the Dosage ?

Tablet - dosage

Tablet – dosage

Tri-Sprintec is a 28-day regimen of tablets, as a contraceptive take one active tablet daily at the same time for 21 days and then take one inactive tablet daily at the same time for next 7 days.

Tri-Sprintec active tablets are gray (Day 1 to Day 7), light blue (Day 8 to Day 15) and blue (Day 16 to Day 21) and inactive tablets are white (Day 22 to 28).

What are the precautions I need to take ?

  • Take this medicine only if prescribed by the doctor
  • Take full course of treatment
  • Do not take this medicinal product after the expiry date stated on the carton package
  • Tell your doctor if you are taking any medicine
  • Tell your doctor if you are suffering from any disease
  • Keep this medicine out of the reach of children.

Don’t take this medicine if  :

  • You are allergic to any of the ingredients of this medicine or any of their excipients
  • You have a history of blood clots
  • You suspect having, currently are suffering or have a history of breast cancer, cancer of vagina, cervical cancer
  • You have any heart related problems including high blood pressure.
  • You have migraine with aura
  • You have abnormal vaginal bleeding without a known cause
  • You are pregnant or if you think you may be pregnant


Is it safe to take If I am pregnant ?

No, This drug is not safe to administer to pregnant women. Estradiol / norgestimate been assigned to pregnancy category X by the FDA, which implies that Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Is it safe to take if I am breast feeding ?

Tri sprintec may affect the quality and quantity of the breast milk, So, it is not advised to administer this drug to lactating mothers, unless advised by the doctor otherwise.

Can this medicine be given to Children and Infants ?

This drug should be kept out of sight and reach of children and infants.

Is Tri sprintec available as an over the counter (OTC) product?

No, This drug is not available as an over the counter product and requires a prescription from a doctor.

Frequently asked questions

can Tri sprintec , cause breast cancer ?

No, there are no reported cases of breast cancer caused due to this drug, but do not take this drug, if you have any history of breast cancer.

I take adderall , can I take Tri sprintec ?

No interactions have been observed between these drugs , so it is safe to consume both simultaneously

Can I take Oxcarbazepine, while on Tri sprintec ?

No, both norgestimate and ethinyl estradiol have major interactions with Oxcarbazepine and Oxcarbazepine may reduce the blood levels and effects of both norgestimate and ethinyl estradiol, ask your doctor for a prescription of different medicine.


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